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Case of the Month - November 2015

Case of the Month - November 2015

A 35-year-old pregnant nurse who works on a general medical ward submits a letter to the hospital administration from her treating physician.

The letter states that ‘I have been treating this patient for four years, and she is a known carrier of hepatitis B virus. She should be withdrawn from all nursing duties that require direct contact with patients and should be redeployed appropriately’.

The nurse is 20 weeks pregnant; she is generally in good health, and has had an uneventful pregnancy to date.

She supplies a copy of a laboratory report with results of hepatitis A, B, and C virus investigations (performed two weeks prior) as well as evidence that Hepatitis B surface antigen was positive 8 months prior.

The results are as follows:
Hepatitis A IgGPositive
Hepatitis B sAg (HBsAg)Positive
Hepatitis B cIgM (Anti-HBc IgM)Negative
Hepatitis B eAg (HBeAg)Negative
Hepatitis B eAb (Anti-HBe)Positive
Hepatitis B virus DNA* (HBV DNA)Not detected
Hepatitis C AbNegative

*Comment on laboratory report: linear reportable range of assay used is 20 – 170 000 000 IU/mL

Question 1
How do you interpret the hepatitis B virus (HBV) serology and PCR results?

Continue to Answer 1