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Case of the Month - March 2011

Frans Radebe
National Institute for Communicable Diseases

A 28 years old HIV-infected man presented at a Sexually Transmitted Infections (STIs) clinic with a giant wart of 4 years duration. Genital examination revealed the giant wart (figure 1) on the shaft of his penis.

Figure 1: Giant genital wart of the shaft penis

RPR for syphilis was negative, as was urine PCR for other STIs except Trichomonas vaginalis, which was positive. His CD4 count was 74 cells/mm3. A biopsy sample taken from the giant wart was PCR positive for HPV-6, 11, 55, 58, 59, 68, 73, 83 and cp6108.

The patient was referred for the commencement of antiretroviral.

Question 1: What is the likely diagnosis and what are the clinical features of this lesion?

Continue to Answer 1